Kpv 5mg

KPV (Lys–Pro–Val) is a tripeptide derived from the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH 11–13), used in experimental research to investigate melanocortin-related signalling and inflammation-associated cellular pathways.

Description & Mechanism

KPV is a synthetic tripeptide corresponding to amino acids 11–13 of α-melanocyte-stimulating hormone (α-MSH). It represents the minimal bioactive fragment commonly utilised in research settings to investigate melanocortin-associated signalling independently of the full-length peptide.

In biochemical and cellular research systems, KPV has been studied for its interactions with melanocortin-related pathways and downstream intracellular signalling mechanisms associated with immune modulation and inflammatory responses. Experimental studies typically examine receptor-independent and receptor-associated signalling effects, transcriptional responses, and peptide stability under controlled conditions. Observed molecular responses are dependent on experimental design, concentration, and model system, and are used to explore peptide-mediated signalling rather than defined biological or physiological outcomes.